Cefpodoxime Proxetil
Cefpodoxime proxetil is an orally administered, broad-spectrum, semi-synthetic prodrug belonging to the third-generation cephalosporin class of antibiotics. Once absorbed, it is rapidly de-esterified in the gastrointestinal tract to its active metabolite, cefpodoxime. It exhibits bactericidal activity by inhibiting cell wall synthesis in susceptible Gram-positive and Gram-negative bacteria.
Dosage by Body Weight
Dosage depends on the type and severity of infection, patient age, and renal function. Oral tablets should be taken with food to enhance absorption. Oral suspension can be administered with or without food. Complete the full prescribed course even if symptoms resolve earlier.
- Body Weight
- Below 5 kg
- Dose
- Not routine
- Frequency
- Use only if prescribed
- Tracking Notes
- Safety and efficacy in infants younger than 2 months have not been established.
- Body Weight
- 5-7 kg
- Dose
- 25 mg to 35 mg (approx. 2.5 mL to 3.5 mL of 50 mg/5 mL suspension)
- Frequency
- Every 12 hours (twice daily)
- Tracking Notes
- Based on standard pediatric dosing of 10 mg/kg/day divided into two doses. Always confirm with a pediatrician.
- Body Weight
- 8-10 kg
- Dose
- 40 mg to 50 mg (approx. 4 mL to 5 mL of 50 mg/5 mL suspension)
- Frequency
- Every 12 hours (twice daily)
- Tracking Notes
- Use a proper dosing syringe or spoon for accuracy. Do not use household spoons.
- Body Weight
- 11-15 kg
- Dose
- 55 mg to 75 mg (approx. 2.75 mL to 3.75 mL of 100 mg/5 mL suspension)
- Frequency
- Every 12 hours (twice daily)
- Tracking Notes
- Using the 100 mg/5 mL strength helps lower the liquid volume the child needs to swallow.
- Body Weight
- 16-20 kg
- Dose
- 80 mg to 100 mg (approx. 4 mL to 5 mL of 100 mg/5 mL suspension)
- Frequency
- Every 12 hours (twice daily)
- Tracking Notes
- Maximum single pediatric dose is typically 200 mg unless specified otherwise by a doctor.
| Body Weight | Dose | Frequency | Tracking Notes |
|---|---|---|---|
| Below 5 kg | Not routine | Use only if prescribed | Safety and efficacy in infants younger than 2 months have not been established. |
| 5-7 kg | 25 mg to 35 mg (approx. 2.5 mL to 3.5 mL of 50 mg/5 mL suspension) | Every 12 hours (twice daily) | Based on standard pediatric dosing of 10 mg/kg/day divided into two doses. Always confirm with a pediatrician. |
| 8-10 kg | 40 mg to 50 mg (approx. 4 mL to 5 mL of 50 mg/5 mL suspension) | Every 12 hours (twice daily) | Use a proper dosing syringe or spoon for accuracy. Do not use household spoons. |
| 11-15 kg | 55 mg to 75 mg (approx. 2.75 mL to 3.75 mL of 100 mg/5 mL suspension) | Every 12 hours (twice daily) | Using the 100 mg/5 mL strength helps lower the liquid volume the child needs to swallow. |
| 16-20 kg | 80 mg to 100 mg (approx. 4 mL to 5 mL of 100 mg/5 mL suspension) | Every 12 hours (twice daily) | Maximum single pediatric dose is typically 200 mg unless specified otherwise by a doctor. |
Formulation
Purpose
Used to treat a wide variety of mild-to-moderate bacterial infections, including acute otitis media (middle ear infection), pharyngitis/tonsillitis, community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, uncomplicated skin infections, and uncomplicated urinary tract infections.
Generic Name
Cefpodoxime ProxetilBranded Drug Names
Cefpodoxime Proxetil is listed as a generic drug name. Common branded medicines that may contain the same active ingredient include:
Scheduled Drug
Yes. This medicine should be supplied or used only according to applicable prescription and regulatory requirements.